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1

Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

Mingozzi, Federico, High, Katherine A.

Journal:

Nature Reviews Genetics

Year:

2011

Language:

english

File:

PDF, 1018 KB

english, 2011

2

Therapeutic in vivo gene transfer for genetic disease using AAV: progress and challenges

Mingozzi, Federico, High, Katherine A.

Journal:

Nature Reviews Genetics

Year:

2011

File:

PDF, 43 KB

2011

3

Gene Therapy for Hemophilia: The Clot Thickens

High, Katherine A.

Journal:

Human Gene Therapy

Year:

2014

Language:

english

File:

PDF, 876 KB

english, 2014

4

Entering the Modern Era of Gene Therapy

Anguela, Xavier M., High, Katherine A.

Journal:

Annual Review of Medicine

Year:

2019

Language:

english

File:

PDF, 703 KB

english, 2019

5

Gene Therapy

High, Katherine A., Roncarolo, Maria G.

Journal:

New England Journal of Medicine

Year:

2019

Language:

english

File:

PDF, 1.80 MB

english, 2019

6

PEG-modulated column chromatography for purification of recombinant adeno-associated virus serotype 9

Jingmin Zhou, Xiao Yang, J. Fraser Wright, Katherine A. High, Linda Couto, Guang Qu

Journal:

Journal of Virological Methods

Year:

2011

Language:

english

File:

PDF, 865 KB

english, 2011

7

Viral vector-mediated RNA interference

Linda B Couto, Katherine A High

Journal:

Current Opinion in Pharmacology

Year:

2010

Language:

english

File:

PDF, 175 KB

english, 2010

8

Shifting the Paradigm: An Assessment of the Quality of Fall Risk Reduction in Nebraska Hospitals

Jones, Katherine J., Venema, Dawn M., Nailon, Regina, Skinner, Anne M., High, Robin, Kennel, Victoria

Journal:

The Journal of Rural Health

Year:

2015

Language:

english

File:

PDF, 210 KB

english, 2015

9

Manufacturing and Regulatory Strategies for Clinical AAV2-hRPE65

Fraser Wright, J., Wellman, Jennifer, High, Katherine

Journal:

Current Gene Therapy

Year:

2010

Language:

english

File:

PDF, 301 KB

english, 2010

10

An edible switch for gene therapy

Anguela, Xavier M, High, Katherine A

Journal:

Nature Biotechnology

Year:

2016

Language:

english

File:

PDF, 329 KB

english, 2016

11

Overcoming the Host Immune Response to Adeno-Associated Virus Gene Delivery Vectors: The Race Between Clearance, Tolerance, Neutralization, and Escape

Mingozzi, Federico, High, Katherine A.

Journal:

Annual Review of Virology

Year:

2017

Language:

english

File:

PDF, 858 KB

english, 2017

12

Oracle or false prophet? Can we predict AAV efficacy based on preexisting antibody titers?

Anguela, Xavier M., High, Katherine A.

Journal:

Research and Practice in Thrombosis and Haemostasis

Year:

2019

Language:

english

File:

PDF, 274 KB

english, 2019

13

Evaluating the use of multiteam systems to manage the complexity of inpatient falls in rural hospitals

Jones, Katherine J., Skinner, Anne, Venema, Dawn, Crowe, John, High, Robin, Kennel, Victoria, Allen, Joseph, Reiter‐Palmon, Roni

Journal:

Health Services Research

Year:

2019

Language:

english

File:

PDF, 978 KB

english, 2019

14

Patient and system factors associated with unassisted and injurious falls in hospitals: an observational study

Venema, Dawn M., Skinner, Anne M., Nailon, Regina, Conley, Deborah, High, Robin, Jones, Katherine J.

Journal:

Year:

2019

File:

PDF, 599 KB

2019

15

Activation of a recombinant human factor VII structural analogue alters its affinity of binding to tissue factor

Sridhara, Sampath, Chaing, Shu, High, Katherine A., Blajchman, Morris A., Clarke, Bryan J.

Journal:

American Journal of Hematology

Year:

1996

Language:

english

File:

PDF, 640 KB

english, 1996

16

Clinical trial opportunities in hemostasis and thrombosis: NHBLI State-of-the-science symposium

Douglas B. Cines, Morris A. Blajchman, Katherine A. High, James B. Bussel, for the State-of-the Science Symposium Hemostasis-Thrombosis Committee

Journal:

American Journal of Hematology

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

17

Insulin resistance due to receptor antibodies: a complication of progressive systemic sclerosis

Philip S. Weinstein, Katherine A. High, A. Joseph D'ercole, J. Charles Jennette

Journal:

Arthritis & Rheumatism

Year:

1980

Language:

english

File:

PDF, 571 KB

english, 1980

18

Diverse IgG subclass responses to adeno-associated virus infection and vector administration

Samuel L. Murphy, Hojun Li, Federico Mingozzi, Denise E. Sabatino, Daniel J. Hui, Shyrie A. Edmonson, Katherine A. High

Journal:

Journal of Medical Virology

Year:

2009

Language:

english

File:

PDF, 477 KB

english, 2009

19

ANlaIII polymorphism within the human factor VII gene

Shu Huey Chaing, Anders Wallmark, Erik Berntorp, Katherine A. High

Journal:

Year:

1994

Language:

english

File:

PDF, 210 KB

english, 1994

20

Adeno-Associated Virus —Mediated Gene Transfer for Hemophilia B

Katherine A. High

Journal:

International Journal of Hematology

Year:

2002

Language:

english

File:

PDF, 111 KB

english, 2002

21

Gene therapy for haemophilia

Samuel L. Murphy, Katherine A. High

Journal:

British Journal of Haematology

Year:

2008

Language:

english

File:

PDF, 123 KB

english, 2008

22

AAV-Mediated Gene Transfer for Hemophilia

KATHERINE A. HIGH

Journal:

Annals of the New York Academy of Sciences

Year:

2001

Language:

english

File:

PDF, 1.15 MB

english, 2001

23

Gene-Based Approaches to the Treatment of Hemophilia

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 90 KB

english, 2002

24

Genetic Approaches to Tissue Engineering : Breakout Session Summary

JEFFREY BONADIO, SAVIO L.C. WOO, KATHERINE HIGH, STEVEN C. GHIVIZZANI, DAVID SCHAFFER, JEFFREY BONADIO

Journal:

Annals of the New York Academy of Sciences

Year:

2002

Language:

english

File:

PDF, 86 KB

english, 2002

25

Gene therapy: The moving finger

High, Katherine A.

Journal:

Year:

2005

Language:

english

File:

PDF, 326 KB

english, 2005

26

10.1038/4743

High, Katherine A., Herzog, Roland W., Yang, Edmund Y., Couto, Linda B., Hagstrom, J. Nathan, Elwell, Dan, Fields, Paul A., Burton, Melissa, Bellinger, Dwight A., Read, Marjorie S., Brinkhous, Kenneth

Journal:

Nature Medicine

Year:

1999

Language:

english

File:

PDF, 204 KB

english, 1999

27

Recombinant adeno-associated virus for muscle directed gene therapy

Fisher, Krishna J., Jooss, Karin, Alston, James, Yang, Yiping, Haecker, Sarah Ehlen, High, Katherine, Pathak, Ravindra, Raper, Steven E., Wilson, James M.

Journal:

Nature Medicine

Year:

1997

File:

PDF, 998 KB

1997

28

Coaxing coagulation with RNA and cell fragments

High, Katherine A

Journal:

Nature Medicine

Year:

2003

Language:

english

File:

PDF, 209 KB

english, 2003

29

Gateway to the diseased brain

Mingozzi, Federico, High, Katherine A

Journal:

Nature Medicine

Year:

2009

Language:

english

File:

PDF, 251 KB

english, 2009

30

Patients Beware: Commercialized Stem Cell Treatments on the Web

Patrick L. Taylor, Roger A. Barker, Karl G. Blume, Elena Cattaneo, Alan Colman, Hongkui Deng, Harold Edgar, Ira J. Fox, Claude Gerstle, Lawrence S.B. Goldstein, Katherine A. High, Andrew Lyall, Robert

Journal:

Year:

2010

Language:

english

File:

PDF, 288 KB

english, 2010

31

Prevalence of the factor V Leiden mutation in children and neonates with thromboembolic disease

J.Nathan Hagstrom, Johannes Walter, Rachel Bluebond-Langner, Joan C. Amatniek, Catherine S. Manno, Katherine A. High

Journal:

The Journal of Pediatrics

Year:

1998

Language:

english

File:

PDF, 40 KB

english, 1998

32

Gene therapy in haematology and oncology

Katherine A High

Journal:

Year:

2000

Language:

english

File:

PDF, 1.38 MB

english, 2000

33

Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

Albert M Maguire, Katherine A High, Alberto Auricchio, J Fraser Wright, Eric A Pierce, Francesco Testa, Federico Mingozzi, Jeannette L Bennicelli, Gui-shuang Ying, Settimio Rossi, Ann Fulton, Kathleen

Journal:

Year:

2009

Language:

english

File:

PDF, 582 KB

english, 2009

34

Advances in Gene Therapy Using Factor VIIa in Hemophilia

Paris Margaritis, Katherine A. High

Journal:

Seminars in Hematology

Year:

2006

Language:

english

File:

PDF, 190 KB

english, 2006

35

ARFI Ultrasound Monitoring of Hemorrhage and Hemostasis In Vivo in Canine Von Willebrand Disease and Hemophilia

Mallory R. Scola, Timothy C. Nichols, Hongtu Zhu, Melissa C. Caughey, Elizabeth P. Merricks, Robin A. Raymer, Paris Margaritis, Katherine A. High, Caterina M. Gallippi

Journal:

Ultrasound in Medicine & Biology

Year:

2011

Language:

english

File:

PDF, 616 KB

english, 2011

36

In Vitro and In Vivo Studies of IgG-derived Treg Epitopes (Tregitopes): A Promising New Tool for Tolerance Induction and Treatment of Autoimmunity

Cousens, Leslie P., Najafian, Nader, Mingozzi, Federico, Elyaman, Wassim, Mazer, Bruce, Moise, Leonard, Messitt, Timothy J., Su, Yan, Sayegh, Mohamed, High, Katherine, Khoury, Samia J., Scott, David W

Journal:

Journal of Clinical Immunology

Year:

2013

Language:

english

File:

PDF, 229 KB

english, 2013

37

Enhanced γ-Carboxylation of Recombinant Factor X Using a Chimeric Construct Containing the Prothrombin Propeptide †

Camire, Rodney M., Larson, Peter J., Stafford, Darrel W., High, Katherine A.

Journal:

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

38

Zidovudine Overdose in an Asymptomatic HIV Seropositive Patient With Hemophilia

Stern, Robert A., van der Horst, Charles M., Hooper, Stephen R., Bloodgood, Karen M., High, Katherine A.

Journal:

Year:

1992

Language:

english

File:

PDF, 479 KB

english, 1992

39

Canine Hemophilia B Resulting from a Point Mutation with Unusual Consequences

James P. Evans, Kenneth M. Brinkhous, Gary D. Brayer, Howard M. Reisner and Katherine A. High

Journal:

Proceedings of the National Academy of Sciences

Year:

1989

Language:

english

File:

PDF, 947 KB

english, 1989

40

Successful Expression of Human Factor IX Following Repeat Administration of an Adenoviral Vector in Mice

Johannes Walter, Qimin You, J. Nathan Hagstrom, Mark Sands and Katherine A. High

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 1.48 MB

english, 1996

41

Stable Gene Transfer and Expression of Human Blood Coagulation Factor IX after Intramuscular Injection of Recombinant Adeno-Associated Virus

Roland W. Herzog, J. Nathan Hagstrom, Szu-Hoo Kung, Shing Jen Tai, James M. Wilson, Krishna J. Fisher and Katherine A. High

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.43 MB

english, 1997

42

Gene Therapy for the Hemophilias

Mark A. Kay and Katherine High

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 720 KB

english, 1999

43

Structure/Function Analyses of Recombinant Variants of Human Factor Xa: Factor Xa Incorporation into Prothrombinase on the Thrombin-Activated Platelet Surface Is Not Mimicked by Synthetic Phospholipid Vesicles †

Larson, Peter J., Camire, Rodney M., Wong, Dore, Fasano, Nicholas C., Monroe, Dougald M., Tracy, Paula B., High, Katherine A.

Journal:

Year:

1998

Language:

english

File:

PDF, 144 KB

english, 1998

44

Safety of Liver Gene Transfer Following Peripheral Intravascular Delivery of Adeno-Associated Virus (AAV)-5 and AAV-6 in a Large Animal Model

Favaro, Patricia, Finn, Jonathan D., Siner, Joshua I., Wright, J. Fraser, High, Katherine A., Arruda, Valder R.

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 634 KB

english, 2011

45

[IEEE 2011 IEEE International Ultrasonics Symposium (IUS) - Orlando, FL, USA (2011.10.18-2011.10.21)] 2011 IEEE International Ultrasonics Symposium - In vivo detection of hemorrhage rate in dog models of hemophilia and VWD and at human femoral arteriotomy by ARFI ultrasound

Scola, Mallory R., Baggesen, Leslie M., Behler, Russel H., Nichols, Timothy C., Zhu, Hongtu, Caughey, Melissa C., Merricks, Elizabeth P., Raymer, Robin A., Margaritis, Paris, High, Katherine A., Galli

Year:

2011

Language:

english

File:

PDF, 636 KB

english, 2011

46

[IEEE 2010 IEEE Ultrasonics Symposium (IUS) - San Diego, CA, USA (2010.10.11-2010.10.14)] 2010 IEEE International Ultrasonics Symposium - ARFI ultrasound for in vivo monitoring of soft-tissue bleeding and hemostasis in a dog model of hemophilia

Scola, Mallory R., Gallippi, Caterina M., Nichols, Timothy C., Caughey, Melissa C., Margaritis, Paris, High, Katherine A.

Year:

2010

Language:

english

File:

PDF, 1.94 MB

english, 2010

47

Effects of Immunosuppression on Circulating Adeno-Associated Virus Capsid-Specific T cells in Humans

Parzych, Elizabeth M., Li, Hua, Yin, Xiangfan, Liu, Qin, Wu, Te-Lang, Podsakoff, Gregory M., High, Katherine A., Levine, Matthew H., Ertl, Hildegund C.J.

Journal:

Human Gene Therapy

Year:

2013

Language:

english

File:

PDF, 1.05 MB

english, 2013

48

Efficient Transfection of Primary Cells in a Canine Hemophilia B Model Using Adenovirus–Polylysine–DNA Complexes

Lozier, Jay N., Thompson, Arthur R., Hu, Ping-Chuan, Read, Marjorie, Brinkhous, Kenneth M., High, Katherine A., Curiel, David T.

Journal:

Human Gene Therapy

Year:

1994

Language:

english

File:

PDF, 3.70 MB

english, 1994

49

Effective gene therapy for haemophilic mice with pathogenic factor IX antibodies

Markusic, David M., Hoffman, Brad E., Perrin, George Q., Nayak, Sushrusha, Wang, Xiaomei, LoDuca, Paul A., High, Katherine A., Herzog, Roland W.

Journal:

EMBO Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 756 KB

english, 2013

50

Cardiac Gene Transfer of Short Hairpin RNA Directed Against Phospholamban Effectively Knocks Down Gene Expression but Causes Cellular Toxicity in Canines

Bish, Lawrence T., Sleeper, Meg M., Reynolds, Caryn, Gazzara, Jeffrey, Withnall, Elanor, Singletary, Gretchen E., Buchlis, George, Hui, Daniel, High, Katherine A., Gao, Guangping, Wilson, James M., Sw

Journal:

Human Gene Therapy

Year:

2011

Language:

english

File:

PDF, 369 KB

english, 2011